NOTE: The Biographical Sketch may not exceed four pages. Follow the formats and instructions below.

A.        Personal Statement

The goal of the proposed research is to study the antimicrobial susceptibility profile of Salmonella typhi, using phenotypic and molecular techniques. Specifically to evaluate the antimicrobial susceptibility pattern of salmonella typhi isolates to ciprofloxacin, ampicillin, co-trimoxazole, chloramphenicol and ceftriaxone using the disk diffusion method; and to detect and characterise the molecular bases of quinolone resistance in

Salmonella typhi isolates through amplification and sequencing of the gyrA gene. I have attended a workshop on DNA extraction and Recombinant Technology organized by the Center for Biotechnology Research and Training, Ahmadu Bello University, Zaria. I have also attended the Welcome Trust Advance Course: Molecular Approaches to Clinical Microbiology in Africa organized by Welcome Trust Advance Foundation, which held in South Africa in 2014. I have just been selected to attend a course on Next Generation Sequencing, which is to be organized by Welcome Trust Advance Foundation in the United Kingdom in the March 2014.  I have the expertise, leadership, and motivation necessary to successfully carry out the proposed work. I also believe that molecular techniques now govern research in medical microbiology, and as such, this project will help build capacity in the use of molecular techniques.

B.        Positions and Honors

Professional service/honour societies:

Member, Medical and Dental Council of Nigeria                               2003-Date

Member, Nigerian Medical Association                                             2003-Date

Member, Association of Resident Doctors in Nigeria                        2007-Date

Member, Association of Pathologists of Nigeria                                2007-Date

C.        Selected Peer-reviewed Publications

1. Aliyu S. Carbapenemase-producing Gram-negative bacteria: An emerging threat to health care in Africa. Ann Nigerian Med 2013; 7:1-2.

2. Aliyu S. Controlling the spread of carbapenemase producing Gram-negative bacteria. Ann Nigerian Med 2013; 7:45-7.

3. Aliyu S. Treating infections caused by carbapenemase producing Gram-negative bacteria. Ann Nigerian Med 2014;8:1-3

4. Aliyu S. Bacterial whole genome sequencing: The future of clinical bacteriology. Ann Nigerian Med 2014;8:51-7

D.        Research Support

I recently completed a research project in fulfillment of part 2 examination of the National Postgraduate Medical College of Nigeria. The project is titled pharyngeal carriage of Neisseria meningitidis among undergraduate students of Ahmadu Bello University, Zaria. The specific objectives of the project were:

1.         To determine the prevalence of pharyngeal carriage of Neisseria meningitidis among undergraduate students in Ahmadu Bello University, Zaria.

2.         To identify the serogroup(s) of the meningococcal strains isolated from the pharynx of undergraduate students of Ahmadu Bello University, Zaria.

3.         To evaluate the antimicrobial susceptibility pattern of meningococcal isolates to ciprofloxacin, rifampicin and ceftriaxone (carriage eradication antibiotics) using their Minimum Inhibitory Concentrations (MICs).

4.         To assess risk factors for pharyngeal carriage of Neisseria meningitidis among undergraduate students of Ahmadu Bello University, Zaria.